Vanessa VanCleef

Vanessa VanCleef is the daughter of Edwin VanCleef and his successor as head of the Defias Brotherhood.

It is revealed in a flashback that Vanessa was present when Edwin VanCleef was killed and decapitated by forces of the Alliance onboard his juggernaught in the Deadmines. After her father's death, Vanessa was adopted by the Saldeans, who were unaware of her identity. They named her Hope and parented her while they watched her grow up over the years. Her identity as Hope Saldean worked to her advantage as she secretly became her father's successor as the leader of the Defias Brotherhood.

Unlike her father, she is not especially skilled in close combat. However, she has very impressive skills in making poisons, especially ones that cause hallucinations or insanity.