Kanto

Kanto is a Pokemon region. It is very, very well known for being the first Pokemon region. It is home to the first 150 Pokemon (plus Mew) as well as many well known cities, landmarks and people, such as the Gym Leaders.

This is the very first place that many veteran Pokemon players and fans have ever played in and it serves as a nostalgic place for those who were kids when Pokemon first released in America.